NLRP3 and Alzheimer disease: The activation of a nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome promotes caspase 1-dependent secretion of proinflammatory cytokines, interleukin (IL)−1β, and IL-18, and has been linked with AD and PD development20,21.