Given that p53 aggregation has been found in numerous tumor cells (Costa et al., 2016; de Oliveira et al., 2015; Levy et al., 2011; Li et al., 2024), it is important to explore the effects of Δ133p53 or Δ160p53 isoforms on the aggregation of FLp53. This evidence concerns the gene TP53 and neoplasm.