MFN2 and cancer: Furthermore, giventhat MFN2 is crucial for mitochondrial fusion, its reduction has beenreported to disrupt mitochondrial morphology and function, includingsuppression of electron transport chain (ETC) complexes required forOXPHOS, consequently forcing cancer cells to rely more heavily onglycolytic ATP production.−,  While previous research suggestedthat OCIAD2 maintains mitochondrial integrity, our data indicated that the relationship between OCIAD2and mitochondrial integrity might be more complex.