To further clarify the role of OCIAD2 expressionin lung adenocarcinoma,the correlation between OCIAD2 expression and 11 clinicopathologicfactors, including age, gender, smoking, differentiation, location,tumor size, lymph node involvement, pleural effusion, the mutationalstatus of EGFR and TP53, and cancer staging, was performed by usingthe Chi-square test. This evidence concerns the gene OCIAD2 and Pleural effusion.