In addition,prior GSEA results based on RNA-seq data from public databases alsodemonstrated enrichment of OCIAD2 in mitochondria-related pathwaysin lung adenocarcinoma, supporting a role for OCIAD2 in mitochondrialregulation. Additionally, the immunopurificationfollowed by quantitative mass spectrometry conducted in HEK293 cellsindicated that OCIAD2 interacts with the electron transport chain(ETC) complexes. In this study, we furtheranalyzed the proteomic data of our cohort to determine the enrichedpathways of the OCIAD2 in lung adenocarcinoma. This evidence concerns the gene OCIAD2 and lung adenocarcinoma.