The Wnt/β-catenin pathway, critical for cancer stem cell (CSC) maintenance, is also disrupted by RSV (IC50 = 0.98 μM for NF-κB inhibition [36]), as shown in breast cancer models where RSV reduces mammosphere formation and induces autophagy via β-catenin suppression [37]. This evidence concerns the gene NFKB1 and breast cancer.