Among these, three genes (HLA-C, CCHCR1, and CDSN) exhibited considerable polymorphism and had coding variations significantly correlated with psoriasis (Capon et al. 2002). HLA-C encodes an MHC class I receptor that contributes to immunological responses by presenting antigens to CD8 + T cells. Here, CCHCR1 is linked to psoriasis.