The levels of IL-4 [462.66 (380.70, 555.82) vs. 498.45 (352.35, 610.67), P = 0.480], IL-13 [224.64 (163.44, 281.77) vs. 229.15 (181.43, 291.04), P = 0.524], TGF-β [492.98 (333.23, 590.89) vs. 468.71 (340.43, 609.11), P = 0.982] did not show significant difference between ALS patients and controls. This evidence concerns the gene IL4 and amyotrophic lateral sclerosis.