Introduction: May–Hegglin anomaly (MHA) is a rare autosomal dominant genetic disorder caused by mutations in the MYH9 gene, leading to the presence of Döhle-like inclusions in neutrophils, macrothrombocytes, and thrombocytopenia. The gene discussed is MYH9; the disease is macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.