("osteoporosis"[All Fields] OR "osteoporosis"[MeSH Terms] OR "osteoporosis, postmenopausal"[MeSH Terms]) AND ("fracture"[All Fields] OR "bone loss"[All Fields] OR "bmd"[All Fields] OR "bone mineral density"[All Fields]) AND ("statins"[All Fields] OR "hmg coa reductase inhibitors"[All Fields] OR "hydroxymethylglutaryl coa reductase inhibitors"[MeSH Terms]). This evidence concerns the gene HMGCR and osteoporosis.