Mesh terms and keywords representing participant (P; “osteoporosis, postmenopausal”, “postmenopausal bone loss”, “osteoporosis, "postmenopausal”, Intervention (I; “Statins”, “HMG CoA reductase inhibitors” and Outcomes (O; “fracture”, “BMD”, “adverse event” and “bone turnover markers”). Here, HMGCR is linked to osteoporosis.