IGF1 and acne: Fitness-oriented supplements, particularly whey protein, are now recognized contributors to acne flares, likely via insulin and IGF-1 pathways. Given the high prevalence of health misinformation online and the lack of regulation surrounding dietary supplements, dermatologists and allied clinicians must prioritize thorough dietary and supplement histories, recognize the skin’s role as an early warning system for nutritional imbalance, and provide evidence-based patient counseling.