Both univariate and multivariate Cox regression analyses indicated that, with the exception of the GSE76019 cohort, CDC20 not only significantly predicted OS, EFS, and PFI but also retained its status as an independent prognostic factor for ACC even after adjusting for clinical covariates such as patient age, gender, and tumor stage (Fig. 4I–J). Here, CDC20 is linked to adrenal cortex carcinoma.