Compared to Scramble BMSC-exosomes, JKAP-knockdown BMSC-exosomes promoted RA-FLS proliferation (p < 0.05) (Figure 3A), suppressed apoptosis (p < 0.05) (Figures 3B and 3C), and facilitated invasion (p < 0.05) (Figures 3D and 3E). This evidence concerns the gene DUSP22 and rheumatoid arthritis.