The Marti TM team found that in mitochondria, lactate dehydrogenase B (LDHB) has a similar principle of action to this pathway, inhibiting mitochondrial ferroptosis by decreasing the ubiquinone (coenzyme Q, CoQ) to ubiquinol (CoQH2) ratio, and that when LDHB is silenced, tumor radiosurgery sensitivity of tumors was increased.24 The gene discussed is LDHB; the disease is neoplasm.