using microarray assay confirmed that the difference gene after knockdown BCAT1 in SKOV3 involve in metabolism, regulation of transcription, transport, signal transduction, cell growth and cell cycle and using a kit-based high-throughput flow injection mass spectrometry approach confirmed that the suppression BCTA1 decrease major metabolite group including sphingolipids, glycerophospholipids and many amino acids, which could provide energy for tumour (75). This evidence concerns the gene BCAT1 and neoplasm.