In the Ant-Ins, we found three downregulated DEGs that recapitulated our mood disorder vs. control findings (see Table S2), including the protein synthesis PSK5 gene and ATP-binding heat shock protein HSPA7 gene (Jabbi et al., 2020a; Pantazatos et al., 2017) and a mitogen-inducible monokine called C-C motif chemokine ligand-4 immunoregulatory and inflammatory CCL4 gene (Table S2A; Fig. 3A and B). This evidence concerns the gene CCL4 and mood disorder.