On Day + 7 and Day + 14 after CLL1 CAR-T infusion, the prediction efficiency of the malnutrition assessment model was high, AUC was greater than 0.8, and CONUT Day + 7 reached the peak (AUC = 0.813), and CONUT Day + 14 (AUC = 0.8009). Here, CLEC12A is linked to nutritional deficiency disease.