KDR and cancer: In addition to the regulation of angiogenesis, autocrine and paracrine VEGF/VEGFR signaling in tumor cells contributes to cancer cell proliferation, survival, induction of the epithelial‐mesenchymal transition, and metastasis.[27, 28] For example, autocrine expression of VEGF has been reported to play a role in hematopoietic malignancies by stimulating the growth and migration of leukemic cells.[29] We, therefore, decided to evaluate the efficacy of our designs on the proliferation of the acute myeloid leukemia cell line, U937, that is sensitive to VEGF.