IL18 and inflammatory bowel disease: Activation and release of the proinflammatory cytokines interleukin (IL)‐1β and IL‐18 mediated by the NLRP3 inflammasome cause cellular damage, leukocyte recruitment and tissue infiltration in several inflammatory and autoimmune diseases, including inflammatory bowel diseases (IBD), multiple sclerosis (MS), and rheumatoid arthritis (RA) [9, 10, 11].