Cross‐sectional analysis of the UK Biobank comparing well‐being (Patient Health Questionnaire‐4; 4–16 points; higher scores indicate greater levels of depressive and anxiety symptoms), number of stressful life events, C‐reactive protein (CRP), and physical activity (International Physical Activity Questionnaire) among pain‐free, acute, and chronic back pain individuals. The gene discussed is CRP; the disease is Anxiety.