To investigate the relationships among VEGF-C, CCL21, LYVE1, and CCR7 in clinical HCC patients, we analyzed the spatial distribution of them based on the previous spatial transcriptomics dataset from HCC patients.28 The Pearson analysis was used to assess the correlation among VEGF-C, CCL21, LYVE1, and CCR7. This evidence concerns the gene LYVE1 and hepatocellular carcinoma.