INS and type 1 diabetes mellitus: The well-known insulin-derived CD8 T cell epitope HLVEALYLV presented by HLA-A*02:0116,41 and reported to be associated with β cell destruction42 was identified in the islet MHC-I peptidome of donors HP-20289 and HP-18101, where it was predicted to be presented by the HLA-A2 family allele A*02:05 and the T1D-associated risk allele A*24:02, respectively.