Single biallelic MCM9 variant carriers were diagnosed with gastric cancer (HP:0012126), a human papillomavirus-unrelated clear cell carcinoma of the cervix (HP:0031522), and melanoma (HP:0012056), whereas a biallelic MCM8 variant carrier was diagnosed with breast cancer (HP:0003002). The gene discussed is MCM8; the disease is cervical clear cell adenocarcinoma.