With the caveat that small sample sizes may create some bias, univariate logistic regression identified female gender, dietary supplement use, virologic control, low eGFR, and normal AST as factors associated with immune recovery, whereas ART-naïve status, formal employment, a low CD4/CD8 ratio, and anaemia were linked to lower odds of a normal CD4 + count (Table 6). The gene discussed is CD4; the disease is anemia.