IL27 and infection: ,27 We chose the 18- to 20-h window for our investigation of the IL-27 producer profile, as we have previously shown that both IL-27 subunits are well expressed in peripheral tissues in the first 24 h postinfection, serum levels peak in this model at 24 h postinfection, and this time period is a critical window for control of the bacterial burden within the tissues and corresponding survival during infection.25