Twelve risk factors of metastatic cPG were identified in the present study: the presence of an SDHB mutation, tumor size and volume on morphological imaging (either CT or MRI), the presence of intra‐tumoral necrosis, lymph node(s), and extracapsular extension on both MRI and CT, the presence of heterogeneous tumor uptake, pathological nodal uptake, and SUVmax tumorSUVmax liver ratio on FDG PET/CT, the sacrifice of noble elements and invasion of adjacent tissues during surgery, and necrosis on histological findings. This evidence concerns the gene SDHB and neoplasm.