Notably, CCNB1 knockdown partially reversed the lipid metabolism enhancement induced by SNRPB overexpression in both HCCLM3 (Fig. 7E) and SK-HEP-1 (Fig. 7F) cells, highlighting the interplay between SNRPB and CCNB1 in regulating lipid metabolism in HCC. The gene discussed is CCNB1; the disease is hepatocellular carcinoma.