Although the parent proteins of several peptide candidates have been found deregulated in neurodegeneration (Barschke et al, 2022; Holtta et al, 2015; Morgan and Carlyle, 2024; Quinn et al, 2023), all peptide sequences are reported here for the first time as being deregulated in neurodegenerative diseases, including NFL. Here, NEFL is linked to neurodegenerative disease.