Others reported the regulation of MAP1B expression and its homologs by proteins known to be implicated in ALS pathology, such as TDP43 and FUS (Coyne et al, 2014; Garone et al, 2023; Majumder et al, 2016; Oberstadt et al, 2018; Romano et al, 2016; Strohm et al, 2022), thus linking MAP1B directly with ALS. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.