Interestingly, in experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), K2P2.1-deficient mice (Kcnk2−/−) developed a worsened disease course with increased CNS immune cell infiltration compared to wild-type (WT) mice1. This evidence concerns the gene KCNK2 and myeloid sarcoma.