Around 15% of PD cases are attributed to a known genetic cause related to the strong genetic risk factor GBA1 (~10%), or pathogenic mutations in SNCA, LRRK2, PRKN, PARK7 (DJ-1), PINK1, and some more rare genes while 85% remain without a known underlying monogenic cause [3,4]. This evidence concerns the gene PINK1 and Parkinson disease.