Our review identified 16 common predictors of MACCEs, including age, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate, bundle branch block and ST elevation (electrocardiogram findings), creatinine, C-reactive protein, glucose, chronic heart failure, Killip class, beta-blocker and statin use, and in-hospital and out-of-hospital cardiac arrest, all of which were significantly associated with a high risk of MACCEs in both ML-based models and CRS models. The gene discussed is CRP; the disease is bundle branch block.