Strikingly, there was higher expression of CD25, CD122, and pSTAT5 in cTreg cells from the lungs of influenza-infected Prdm1-CKO mice than in WT mice (Fig. 2, H to J), as well as higher production of interferon-γ (IFN-γ) and IL-2 but lower production of IL-10 by Prdm1-CKO cTreg cells (fig. This evidence concerns the gene IFNG and influenza.