It has been shown that mice lacking global or thalamic Cav3.1 showed altered slow oscillations and sleep architecture (Anderson et al., 2005; Lee et al., 2004); delayed sleep induction under several anesthetics (i.e. isoflurane, halothane, sevoflurane, and pentobarbital) (Petrenko et al., 2007); and increased resistance to drug-induced absence seizures (Kim et al., 2001). Here, CACNA1G is linked to Generalized non-motor (absence) seizure.