Gene Set Enrichment Analysis (GSEA) corroborated the involvement of genes regulating EMT (Figure 1D), and the involvement of LIN28B in promoting the phenotypic transition of neuroblastoma cells towards a mesenchymal form with increased migratory capacity.[6, 17] Given that 98% of differentially expressed genes were found overexpressed in iLIN28B cells, a hierarchical clustering of overrepresented enriched terms was calculated. This evidence concerns the gene LIN28B and neuroblastoma.