Neurodegeneration has been linked to metal ion transport across disease types including Menkes disease which is directly linked to mutations in Atp7a; other neurodegenerative diseases including, Parkinson’s disease, Alzheimer’s disease, frontal temporal dementia and amyotrophic lateral sclerosis (ALS) (Gale and Aizenman, 2024). This evidence concerns the gene ATP7A and Alzheimer disease.