TSLP and asthma: Furthermore, airway damage increases epithelial permeability, enhancing allergen exposure and promoting the release of alarmins [Interleukin-25 (IL-25), Interleukin-33 (IL-33), and thymic stromal lymphopoietin (TSLP)] by epithelial cells, which in turn induce Th2-high asthma (Gaspar et al., 2020; Gao and Rezaee, 2022).