Baduanjin exercise can improve physical frailty and cognitive function in older adults with CF and may modulate oxidative stress and inflammatory processes by reducing circulating levels of pro-oxidative markers such as MDA and 8-iso-prostaglandin F2α, while increasing levels of the antioxidant enzyme SOD; additionally, the improvement in cognitive function with Baduanjin exercise is mediated by an increase in circulating inflammatory cytokines, specifically IFN-γ and IL-2 (32). The gene discussed is SOD1; the disease is cystic fibrosis.