On OAR4:65,051,183 was found the SNP rs424868378, which was found to be associated with TLB, and close to this SNP is the BBS9 (Bardet–Biedl syndrome 9) gene, a member of a family of genes that cause Bardet–Biedl syndrome, which is characterized by various hypogonadism or genitourinary abnormalities such as a malformed uterus, hydrometrocolpos, and vaginal atresia, resulting in irregular menstrual cycle and polycystic ovaries (Melluso et al., 2023). This evidence concerns the gene BBS9 and hypogonadism.