Other RCC cell lines, such as clear cell renal carcinoma cell line 1 (Caki‐1), human renal cell carcinoma cell line 786‐O (786‐O), and renal cell carcinoma cell line 4 (RCC4), also exhibited TRAIL resistance due to various mechanisms, including overexpression of anti‐apoptotic proteins (Caki‐1), mutations in apoptotic pathways (786‐O), or hypoxia‐related resistance (RCC4). Here, SLC49A4 is linked to renal cell carcinoma.