We focused on several representative genes with important functions in GBM such as CD44, cyclin D1 (CCND1), AXL receptor tyrosine kinase (AXL), integrin subunit alpha 2 (ITGA2), nerve growth factor receptor (NGFR), and caveolin 1 (CAV1)36,53–56. The gene discussed is CAV1; the disease is glioblastoma.