CRH showed a positive effect size in AD but negative in DLB, while NRGN, CRP, and Oligo-SNCA showed negative direction of change in AD but positive in DLB.(Supplementary Table 1, 2) A moderate correlation was observed between AD and FTD (r = 0.48, p = 7.30×10−6). The gene discussed is CRP; the disease is Lewy body dementia.