NEFL and Alzheimer disease: Other highly significant proteins for AD included GFAP (βAD= 0.16; PAD= 9.63×10−83), p-tau231 (βAD= 0.16; pAD= 2.02×10−72), NEFL (βAD= 0.09; pAD= 4.02×10−34) and p-tau181 (PAD= 0.09; pAD= 1.59×10−32; Supplementary Table 1–4).