AFP and neoplasm: The final results exhibited distant metastasis (95% CI: 1.52 (1.18–1.96), p= 0.001), the largest tumor diameter > 50 mm (95% CI: 1.51 (1.20–1.89), p < 0.001), TACE times < 2 (95% CI: 0.66 (0.51–0.85), p= 0.001) and AFP level ≥ 400ng/ml (95% CI: 1.50 (1.20–1.87), p < 0.001) were independent risk factors affecting OS (Table 3).