PRPS1 and Hodgkins lymphoma: Compared to healthy participants, five patients with HL exhibited PRS-I activity ranging from 45.68–85.29 nmol/mL·h, while unaffected heterozygotes and hemizygotes showed higher PRS-I activity (277.87–331.22 nmol/mL·h), which was markedly higher than those with HL (p < 0.05, ANOVA), but still lower than the healthy persons (p < 0.05, ANOVA).