CSNK2A1 and autism spectrum disorder: Since CSNK2A1 is recognized as an autism-related gene with the highest gene score of 1 in the SFARI database,2 we compared the frequency of autism-spectrum disorder (ASD) between loop and non-loop individuals; non-loop individuals were more likely to report ASD (6/8) than loop individuals (13/40) (Figure 6F, p = 0.04).