TNF and bronchiectasis: (2017), treatment with 80 mg/day of atorvastatin (considered high-intensive statin therapy) for three months reduced serum levels of interleukin 8 (IL-8), tumor necrosis factor (TNF), intercellular adhesion molecule 1 (ICAM1), C-reactive protein (CRP), and neutrophil counts in patients with bronchiectasis (20).