APOE and brain disorder: The relationship with lower Aβ PET Centiloids remained when examined specifically in night workers (rather than night or shift workers) (−9.8 Centiloids, 95% CI −15.8, −3.6; P = 0.003), after adjusting for childhood cognition (−9.3 Centiloids, 95% CI −14.5, −3.9; P = 0.001), without adjustment for APOE ɛ4 carrier status (−8.0 Centiloids, 95% CI −13.4, −2.4; P = 0.006), and after excluding those with significant brain disorders from the analysis (−8.8 Centiloids, 95% CI −14.2, −3.1, P = 0.003).