Mistry K et al., in 2003, conducted a meta-analysis of 13 studies, in which a PSA value of more than 4 ng/ml was taken as the cut-off and detected to have sensitivity, specificity, and PPV of 72.1%, 93.2%, and 25.1%, correspondingly, for prostate cancer [7]. Here, KLK3 is linked to prostate carcinoma.