About 30% of cystic kidney disease variants were found in patients aged > 75 years, including variants in 4 genes causing ADPKD-like disease spectrum (ALG5, ALG9, DNAJB11, and monoallelic IFT140) (Figure 3 and Supplementary Table S2). The gene discussed is DNAJB11; the disease is autosomal dominant polycystic kidney disease.