Immunohistochemical results showed that among the 8 CRGs: CEP55, FAM111B, MRPL3, MET, and KNSTRN had higher protein expression in pancreatic cancer tissues, while on the contrary, the protein expression of DHX30 in normal pancreas was significantly higher than that in pancreatic cancer tissues (Figure 6B). This evidence concerns the gene KNSTRN and familial pancreatic carcinoma.