EGFR and glioblastoma: Further, studies of [111In]In-DOTA-panitumumab-AuNPs (Additional file 1: Fig. S6) showed selective binding to the cell surface and internalization into the cytoplasm and nucleus for EGFR-overexpressing U251-Luc cells compared to U87MG cells with low EGFR (Additional file 1: Fig. S1) or or murine GL261 glioblastoma cells with negligible EGFR (Guo et al. 2019).