To target EGFR overexpressed on U251-Luc human GBM cells (Additional file 1: Fig. S1), [197Hg]Hg-AuNPs were conjugated to panitumumab through forming a gold-thiol bond with a cysteine in panitumumab as reported for conjugation of EGF to AuNPs (Song et al., 2017). This evidence concerns the gene EGFR and glioblastoma.