Notably, a significant proportion of these newly discovered genes have emerged as key players in the endolysosomal pathway, shedding light on the central role of endolysosomes in the development and progression of PD [19]. In a cohort of Belgian patients with PD and dementia with Lewy bodies (DLB) compound heterozygous missense variants were identified in a lysosomal gene from the P4-ATPase family known as ATP10B, which was proposed as a novel candidate genetic risk factor in PD. The gene discussed is ATP10B; the disease is Parkinson disease.