ALKBH3 and cancer: The regulators associated with m1A modifications encompass a range of proteins, including TRMT6/TRMT61A, ALKBH1, ALKBH3, and the YTH-domain family proteins.253 Emerging evidence suggests that the levels of m1A methylation and the expression of m1A-related RNAs could serve as innovative biomarkers for predicting cancer prognosis.