YTHDF3 and familial pancreatic carcinoma: It has been revealed to promote the translation of Integrin subunit α 6 (ITGA6) mRNA, which is instrumental in the development of bladder cancer.250,251 In the context of pancreatic cancer, YTHDF3’s role is further underscored by its interaction with ZDHHC20, which mediates S-palmitoylation of YTHDF3.