However, no demethylase for m7G has been identified to date.305 A growing body of evidence implicates m7G in the development of various human diseases, particularly cancer.306 Disruptions in m7G levels are intricately linked to the onset and advancement of malignancies, as they regulate the transcription of numerous oncogenes and tumor suppressor genes.307 Abnormalities in m7G modification may lead to changes in tumor cell proliferation, migration and invasion.308. The gene discussed is MBD2; the disease is cancer.