HOTAIR and neoplasm: LncRNAs implicated in breast cancer include HOTAIR, ANRIL, ZFAS1, HOTAIRM1, PVT1, MALAT1, and LNP1, among others.332 HOTAIR suppresses tumor suppressor genes like PGR, PCDH10, PCDHB5, and JAM2, promoting breast cancer development, and is overexpressed in colorectal, hepatocellular, gastrointestinal, and NSCLC.333–335 Besides, ANRIL is also upregulated in breast cancer.