Decreased expression of FTO protein is related to poor clinical outcomes in gastric cancer patients, suggesting that FTO exerts a regulatory influence on the progression and metastatic dissemination of gastric cancer.219 FTO is elevated expression in NSCLC tissues and cellular models, while m6A content is reduced.220,221 On the other hand, the antitumor effects of FTO have been gradually explored. This evidence concerns the gene FTO and gastric cancer.