Nonetheless, some research has suggested that elevated TET3 expression in prostate cancer may correlate with a poorer prognosis, emphasizing the intricate and context-dependent roles of TET enzymes in the realm of cancer biology.290 Additionally, research has indicated that ALKBH1 is upregulated in a variety of cancers, including gastric, head and neck, and liver cancers. This evidence concerns the gene TET3 and cancer.